Journal: Biomedicines
Article Title: Silencing of LLGL2 Suppresses the Estradiol-Induced BPH-1 Cell Proliferation through the Regulation of Autophagy
doi: 10.3390/biomedicines10081981
Figure Lengend Snippet: LLGL2 is highly expressed in testosterone-induced rat benign prostatic hyperplasia (BPH) in vivo. Representative photographs of immunostaining for LLGL2 ( A – D ). Prostate of control group; magnifications: ×100, scale bar = 100 μm ( A ) and magnifications: ×200, scale bar = 20 μm ( B ). Prostate of BPH group; magnifications: ×100, scale bar = 100 μm ( C ) and magnifications: ×200, scale bar = 20 μm ( D ). ( E ) LLGL2 protein expression in testosterone-induced rat BPH prostate tissue by Western blotting. ( F ) Graphical representation of the ratio of LLGL2 to β-actin. Values are expressed as the means ± standard deviation; *** p < 0.001 versus control group.
Article Snippet: Human BPH-derived prostate epithelial cell lines (BPH-1) were purchased from Merck Millipore (Merck, Kenilworth, NJ, USA).
Techniques: In Vivo, Immunostaining, Expressing, Western Blot, Standard Deviation